Sunday, March 29, 2009

SNPs in the human genome: Hot paper in biology

The article "A second generation human haplotype map of over 3.1 million SNPs," by the International HapMap Consortium (K.A. Frazer, et al.), Nature, 449(7164): 854-61, 18 October 2007, has made it to the Hot Papers Database in the area of Biology due to its high citation rate during November-December 2008. The paper was cited 61 times in current journal articles indexed by Thomson Reuters in those months. Notably, during that period, only two other biology papers published in the last two years (aside from reviews) attracted higher citation totals.

[Source: ScienceWatch]

I normally do not encourage "excitement" about citations and journal statistics such as the Impact Factor, but I did a lot of reading on SNPs and the HapMap last year, and I thought it was interesting to highlight this article as the HapMap has important implications for the prevention, diagnosis, and treatment of human diseases.

Do you know what the HapMap is? If you don't, take a look at this site [What is the HapMap?]
It's a short (~2 pages) and very illustrative article explaining the basics about the whole project.